Gossip Girl has got a couple of things going against it. One, it's on "The CW", which is bad enough. Two, I can't get a signal from the CW tower where I live, which means I don't get to watch anything on that channel in HD. Three, it's about, and kind of targeted towards, teenagers. I've watched high school shows before (most recently Veronica Mars), but I always have a tough time explaining to my wife why I'm spending so much of my time watching TV shows about underage girls.
That said, I thought the show was really well done. The characters that were supposed to be bad were almost mustache-twirlingly bad, but the characters that were supposed to be likable really genuinely were. The lead girl, Serena Van Der Something was very sympathetic, and I really felt for her and how difficult her (crazy rich) life was.
I was completely caught off guard by this show. I really didn't expect it to be any good at all. I don't know if I'll keep it for good, but I'll definitely move on to a second episode.